Biotechnological Applications in Medicine
BIOXII12: BIOTECHNOLOGY AND ITS APPLICATIONS

347738 Select the correct answer
i. Using rDNA technique insulin assembled into a mature form, which does not contain any extra stretch called A-peptide.
ii. In 1983, Eli Lilly an American company prepared two DNA sequences corresponding to \(\mathrm{A}\) and \(\mathrm{B}\), chains of human insulin and introduced them in plasmids of
E. coli
to produce insulin chains.

1 Only i is correct
2 Only ii is correct
3 Both are correct
4 None are correct
BIOXII12: BIOTECHNOLOGY AND ITS APPLICATIONS

347739 Statement A :
Human insulin is made up of 50 amino acids arranged in two polypeptide
Statement B :
C-peptide is present in the mature insulin

1 Statement A is correct but Statement B is incorrect.
2 Statement A is incorrect but Statement B is correct.
3 Both statements are correct.
4 Both Statements are incorrect.
BIOXII12: BIOTECHNOLOGY AND ITS APPLICATIONS

347740 Which of the following companies prepared human insulin and in which year?

1 Ali Lilly, 1983
2 Eli Lilly, 1983
3 Ali Lillie, 1983
4 Eli Lilly, 1986
BIOXII12: BIOTECHNOLOGY AND ITS APPLICATIONS

347741 The main challenge for production of insulin using rDNA techniques was getting insulin assembled into a mature form. Why was it so?

1 \(\mathrm{B}\) - peptide is absent in mature insulin
2 \(\mathrm{B}\) - peptide is added to proinsulin
3 \(\mathrm{C}\) - peptide is absent in mature insulin
4 \(\mathrm{C}\) - peptide is added to proinsulin
BIOXII12: BIOTECHNOLOGY AND ITS APPLICATIONS

347742 Statements related to human insulin are given below :
Which statement(s) is / are correct about genetically engineered insulin?
I. Pro-hormone insulin contain extra stretch of C-peptide
II. A-peptide and B-peptide chains of insulin were produced separately in E. coli, extracted and combined by creating disulphide bond between them.
III. Insulin used for treating Diabetes was extracted from Cattles and Pigs
IV. Pro-hromone insulin needs to be processed for converting into a mature and functional hormone.
V. Some patients develop allergic reactions to the foreign insulin.
Choose the most appropriate answer from the options given below:

1 II only
2 III and IV only
3 III, IV and V only
4 I, II and IV only
BIOXII12: BIOTECHNOLOGY AND ITS APPLICATIONS

347738 Select the correct answer
i. Using rDNA technique insulin assembled into a mature form, which does not contain any extra stretch called A-peptide.
ii. In 1983, Eli Lilly an American company prepared two DNA sequences corresponding to \(\mathrm{A}\) and \(\mathrm{B}\), chains of human insulin and introduced them in plasmids of
E. coli
to produce insulin chains.

1 Only i is correct
2 Only ii is correct
3 Both are correct
4 None are correct
BIOXII12: BIOTECHNOLOGY AND ITS APPLICATIONS

347739 Statement A :
Human insulin is made up of 50 amino acids arranged in two polypeptide
Statement B :
C-peptide is present in the mature insulin

1 Statement A is correct but Statement B is incorrect.
2 Statement A is incorrect but Statement B is correct.
3 Both statements are correct.
4 Both Statements are incorrect.
BIOXII12: BIOTECHNOLOGY AND ITS APPLICATIONS

347740 Which of the following companies prepared human insulin and in which year?

1 Ali Lilly, 1983
2 Eli Lilly, 1983
3 Ali Lillie, 1983
4 Eli Lilly, 1986
BIOXII12: BIOTECHNOLOGY AND ITS APPLICATIONS

347741 The main challenge for production of insulin using rDNA techniques was getting insulin assembled into a mature form. Why was it so?

1 \(\mathrm{B}\) - peptide is absent in mature insulin
2 \(\mathrm{B}\) - peptide is added to proinsulin
3 \(\mathrm{C}\) - peptide is absent in mature insulin
4 \(\mathrm{C}\) - peptide is added to proinsulin
BIOXII12: BIOTECHNOLOGY AND ITS APPLICATIONS

347742 Statements related to human insulin are given below :
Which statement(s) is / are correct about genetically engineered insulin?
I. Pro-hormone insulin contain extra stretch of C-peptide
II. A-peptide and B-peptide chains of insulin were produced separately in E. coli, extracted and combined by creating disulphide bond between them.
III. Insulin used for treating Diabetes was extracted from Cattles and Pigs
IV. Pro-hromone insulin needs to be processed for converting into a mature and functional hormone.
V. Some patients develop allergic reactions to the foreign insulin.
Choose the most appropriate answer from the options given below:

1 II only
2 III and IV only
3 III, IV and V only
4 I, II and IV only
BIOXII12: BIOTECHNOLOGY AND ITS APPLICATIONS

347738 Select the correct answer
i. Using rDNA technique insulin assembled into a mature form, which does not contain any extra stretch called A-peptide.
ii. In 1983, Eli Lilly an American company prepared two DNA sequences corresponding to \(\mathrm{A}\) and \(\mathrm{B}\), chains of human insulin and introduced them in plasmids of
E. coli
to produce insulin chains.

1 Only i is correct
2 Only ii is correct
3 Both are correct
4 None are correct
BIOXII12: BIOTECHNOLOGY AND ITS APPLICATIONS

347739 Statement A :
Human insulin is made up of 50 amino acids arranged in two polypeptide
Statement B :
C-peptide is present in the mature insulin

1 Statement A is correct but Statement B is incorrect.
2 Statement A is incorrect but Statement B is correct.
3 Both statements are correct.
4 Both Statements are incorrect.
BIOXII12: BIOTECHNOLOGY AND ITS APPLICATIONS

347740 Which of the following companies prepared human insulin and in which year?

1 Ali Lilly, 1983
2 Eli Lilly, 1983
3 Ali Lillie, 1983
4 Eli Lilly, 1986
BIOXII12: BIOTECHNOLOGY AND ITS APPLICATIONS

347741 The main challenge for production of insulin using rDNA techniques was getting insulin assembled into a mature form. Why was it so?

1 \(\mathrm{B}\) - peptide is absent in mature insulin
2 \(\mathrm{B}\) - peptide is added to proinsulin
3 \(\mathrm{C}\) - peptide is absent in mature insulin
4 \(\mathrm{C}\) - peptide is added to proinsulin
BIOXII12: BIOTECHNOLOGY AND ITS APPLICATIONS

347742 Statements related to human insulin are given below :
Which statement(s) is / are correct about genetically engineered insulin?
I. Pro-hormone insulin contain extra stretch of C-peptide
II. A-peptide and B-peptide chains of insulin were produced separately in E. coli, extracted and combined by creating disulphide bond between them.
III. Insulin used for treating Diabetes was extracted from Cattles and Pigs
IV. Pro-hromone insulin needs to be processed for converting into a mature and functional hormone.
V. Some patients develop allergic reactions to the foreign insulin.
Choose the most appropriate answer from the options given below:

1 II only
2 III and IV only
3 III, IV and V only
4 I, II and IV only
BIOXII12: BIOTECHNOLOGY AND ITS APPLICATIONS

347738 Select the correct answer
i. Using rDNA technique insulin assembled into a mature form, which does not contain any extra stretch called A-peptide.
ii. In 1983, Eli Lilly an American company prepared two DNA sequences corresponding to \(\mathrm{A}\) and \(\mathrm{B}\), chains of human insulin and introduced them in plasmids of
E. coli
to produce insulin chains.

1 Only i is correct
2 Only ii is correct
3 Both are correct
4 None are correct
BIOXII12: BIOTECHNOLOGY AND ITS APPLICATIONS

347739 Statement A :
Human insulin is made up of 50 amino acids arranged in two polypeptide
Statement B :
C-peptide is present in the mature insulin

1 Statement A is correct but Statement B is incorrect.
2 Statement A is incorrect but Statement B is correct.
3 Both statements are correct.
4 Both Statements are incorrect.
BIOXII12: BIOTECHNOLOGY AND ITS APPLICATIONS

347740 Which of the following companies prepared human insulin and in which year?

1 Ali Lilly, 1983
2 Eli Lilly, 1983
3 Ali Lillie, 1983
4 Eli Lilly, 1986
BIOXII12: BIOTECHNOLOGY AND ITS APPLICATIONS

347741 The main challenge for production of insulin using rDNA techniques was getting insulin assembled into a mature form. Why was it so?

1 \(\mathrm{B}\) - peptide is absent in mature insulin
2 \(\mathrm{B}\) - peptide is added to proinsulin
3 \(\mathrm{C}\) - peptide is absent in mature insulin
4 \(\mathrm{C}\) - peptide is added to proinsulin
BIOXII12: BIOTECHNOLOGY AND ITS APPLICATIONS

347742 Statements related to human insulin are given below :
Which statement(s) is / are correct about genetically engineered insulin?
I. Pro-hormone insulin contain extra stretch of C-peptide
II. A-peptide and B-peptide chains of insulin were produced separately in E. coli, extracted and combined by creating disulphide bond between them.
III. Insulin used for treating Diabetes was extracted from Cattles and Pigs
IV. Pro-hromone insulin needs to be processed for converting into a mature and functional hormone.
V. Some patients develop allergic reactions to the foreign insulin.
Choose the most appropriate answer from the options given below:

1 II only
2 III and IV only
3 III, IV and V only
4 I, II and IV only
BIOXII12: BIOTECHNOLOGY AND ITS APPLICATIONS

347738 Select the correct answer
i. Using rDNA technique insulin assembled into a mature form, which does not contain any extra stretch called A-peptide.
ii. In 1983, Eli Lilly an American company prepared two DNA sequences corresponding to \(\mathrm{A}\) and \(\mathrm{B}\), chains of human insulin and introduced them in plasmids of
E. coli
to produce insulin chains.

1 Only i is correct
2 Only ii is correct
3 Both are correct
4 None are correct
BIOXII12: BIOTECHNOLOGY AND ITS APPLICATIONS

347739 Statement A :
Human insulin is made up of 50 amino acids arranged in two polypeptide
Statement B :
C-peptide is present in the mature insulin

1 Statement A is correct but Statement B is incorrect.
2 Statement A is incorrect but Statement B is correct.
3 Both statements are correct.
4 Both Statements are incorrect.
BIOXII12: BIOTECHNOLOGY AND ITS APPLICATIONS

347740 Which of the following companies prepared human insulin and in which year?

1 Ali Lilly, 1983
2 Eli Lilly, 1983
3 Ali Lillie, 1983
4 Eli Lilly, 1986
BIOXII12: BIOTECHNOLOGY AND ITS APPLICATIONS

347741 The main challenge for production of insulin using rDNA techniques was getting insulin assembled into a mature form. Why was it so?

1 \(\mathrm{B}\) - peptide is absent in mature insulin
2 \(\mathrm{B}\) - peptide is added to proinsulin
3 \(\mathrm{C}\) - peptide is absent in mature insulin
4 \(\mathrm{C}\) - peptide is added to proinsulin
BIOXII12: BIOTECHNOLOGY AND ITS APPLICATIONS

347742 Statements related to human insulin are given below :
Which statement(s) is / are correct about genetically engineered insulin?
I. Pro-hormone insulin contain extra stretch of C-peptide
II. A-peptide and B-peptide chains of insulin were produced separately in E. coli, extracted and combined by creating disulphide bond between them.
III. Insulin used for treating Diabetes was extracted from Cattles and Pigs
IV. Pro-hromone insulin needs to be processed for converting into a mature and functional hormone.
V. Some patients develop allergic reactions to the foreign insulin.
Choose the most appropriate answer from the options given below:

1 II only
2 III and IV only
3 III, IV and V only
4 I, II and IV only