Biotechnological Applications in Medicine
NEET Test Series from KOTA - 10 Papers In MS WORD WhatsApp Here
BIOXII12: BIOTECHNOLOGY AND ITS APPLICATIONS

347746 Which of the following statements is / are true about genetically engineered insulin?
I. Its name is humulin
II. It was manufactured by American firm Eli Lilly
III. Animal insulin is not identical to human insulin. Actually insulin contain A and B peptide chains.
IV. It is produced by the fermentation of appropriate recombinant
E. coli
clones,

1 I, II
2 II, III
3 I, II, III
4 I, II, III, IV
BIOXII12: BIOTECHNOLOGY AND ITS APPLICATIONS

347735 Assertion :
Using biotechnology human insulin can be produced into bacterial cells.
Reason :
To produce human insulin the \(\mathrm{A}, \mathrm{B}\) and \(\mathrm{C}\) polypeptides of the human insulin are produced in the bacterial cells, separately extracted and combined by creating disulfide bonds.

1 Both Assertion and Reason are correct and Reason is the correct explanation of the Assertion.
2 Both Assertion and Reason are correct but Reason is not the correct explanation of the Assertion.
3 Assertion is correct but Reason is incorrect.
4 Both Assertion and Reason are incorrect.
BIOXII12: BIOTECHNOLOGY AND ITS APPLICATIONS

347736 Some of the steps involved in the production of Humulin are given below. Choose the correct sequence
(i) Synthesis of gene (DNA) for human insulin artificially
(ii) Culturing recombinant
E.coli
in bioreactors
(iii) Purification of humulin
(iv) Insertion of human insulin gene into plasmid
(v) Introduction of recombinant plasmid into
E.coli
(vi) Extraction of recombinant gene product from
E.coli

1 i, iii, v, vi, ii, iv
2 ii, i, iv, iii, v, vi
3 iii, v, ii, i, vi, iv
4 i, iv, v, ii, vi, iii
BIOXII12: BIOTECHNOLOGY AND ITS APPLICATIONS

347737 What is the merit of using the recombinant therapeutics instead of bovine insulin (from cow) in diabetic patients?

1 It leads to severe hyperglycemia
2 It is expensive
3 Do not induce unwanted immunological responses
4 It leads to severe hypoglycemia
BIOXII12: BIOTECHNOLOGY AND ITS APPLICATIONS

347746 Which of the following statements is / are true about genetically engineered insulin?
I. Its name is humulin
II. It was manufactured by American firm Eli Lilly
III. Animal insulin is not identical to human insulin. Actually insulin contain A and B peptide chains.
IV. It is produced by the fermentation of appropriate recombinant
E. coli
clones,

1 I, II
2 II, III
3 I, II, III
4 I, II, III, IV
BIOXII12: BIOTECHNOLOGY AND ITS APPLICATIONS

347735 Assertion :
Using biotechnology human insulin can be produced into bacterial cells.
Reason :
To produce human insulin the \(\mathrm{A}, \mathrm{B}\) and \(\mathrm{C}\) polypeptides of the human insulin are produced in the bacterial cells, separately extracted and combined by creating disulfide bonds.

1 Both Assertion and Reason are correct and Reason is the correct explanation of the Assertion.
2 Both Assertion and Reason are correct but Reason is not the correct explanation of the Assertion.
3 Assertion is correct but Reason is incorrect.
4 Both Assertion and Reason are incorrect.
BIOXII12: BIOTECHNOLOGY AND ITS APPLICATIONS

347736 Some of the steps involved in the production of Humulin are given below. Choose the correct sequence
(i) Synthesis of gene (DNA) for human insulin artificially
(ii) Culturing recombinant
E.coli
in bioreactors
(iii) Purification of humulin
(iv) Insertion of human insulin gene into plasmid
(v) Introduction of recombinant plasmid into
E.coli
(vi) Extraction of recombinant gene product from
E.coli

1 i, iii, v, vi, ii, iv
2 ii, i, iv, iii, v, vi
3 iii, v, ii, i, vi, iv
4 i, iv, v, ii, vi, iii
BIOXII12: BIOTECHNOLOGY AND ITS APPLICATIONS

347737 What is the merit of using the recombinant therapeutics instead of bovine insulin (from cow) in diabetic patients?

1 It leads to severe hyperglycemia
2 It is expensive
3 Do not induce unwanted immunological responses
4 It leads to severe hypoglycemia
BIOXII12: BIOTECHNOLOGY AND ITS APPLICATIONS

347746 Which of the following statements is / are true about genetically engineered insulin?
I. Its name is humulin
II. It was manufactured by American firm Eli Lilly
III. Animal insulin is not identical to human insulin. Actually insulin contain A and B peptide chains.
IV. It is produced by the fermentation of appropriate recombinant
E. coli
clones,

1 I, II
2 II, III
3 I, II, III
4 I, II, III, IV
BIOXII12: BIOTECHNOLOGY AND ITS APPLICATIONS

347735 Assertion :
Using biotechnology human insulin can be produced into bacterial cells.
Reason :
To produce human insulin the \(\mathrm{A}, \mathrm{B}\) and \(\mathrm{C}\) polypeptides of the human insulin are produced in the bacterial cells, separately extracted and combined by creating disulfide bonds.

1 Both Assertion and Reason are correct and Reason is the correct explanation of the Assertion.
2 Both Assertion and Reason are correct but Reason is not the correct explanation of the Assertion.
3 Assertion is correct but Reason is incorrect.
4 Both Assertion and Reason are incorrect.
BIOXII12: BIOTECHNOLOGY AND ITS APPLICATIONS

347736 Some of the steps involved in the production of Humulin are given below. Choose the correct sequence
(i) Synthesis of gene (DNA) for human insulin artificially
(ii) Culturing recombinant
E.coli
in bioreactors
(iii) Purification of humulin
(iv) Insertion of human insulin gene into plasmid
(v) Introduction of recombinant plasmid into
E.coli
(vi) Extraction of recombinant gene product from
E.coli

1 i, iii, v, vi, ii, iv
2 ii, i, iv, iii, v, vi
3 iii, v, ii, i, vi, iv
4 i, iv, v, ii, vi, iii
BIOXII12: BIOTECHNOLOGY AND ITS APPLICATIONS

347737 What is the merit of using the recombinant therapeutics instead of bovine insulin (from cow) in diabetic patients?

1 It leads to severe hyperglycemia
2 It is expensive
3 Do not induce unwanted immunological responses
4 It leads to severe hypoglycemia
BIOXII12: BIOTECHNOLOGY AND ITS APPLICATIONS

347746 Which of the following statements is / are true about genetically engineered insulin?
I. Its name is humulin
II. It was manufactured by American firm Eli Lilly
III. Animal insulin is not identical to human insulin. Actually insulin contain A and B peptide chains.
IV. It is produced by the fermentation of appropriate recombinant
E. coli
clones,

1 I, II
2 II, III
3 I, II, III
4 I, II, III, IV
BIOXII12: BIOTECHNOLOGY AND ITS APPLICATIONS

347735 Assertion :
Using biotechnology human insulin can be produced into bacterial cells.
Reason :
To produce human insulin the \(\mathrm{A}, \mathrm{B}\) and \(\mathrm{C}\) polypeptides of the human insulin are produced in the bacterial cells, separately extracted and combined by creating disulfide bonds.

1 Both Assertion and Reason are correct and Reason is the correct explanation of the Assertion.
2 Both Assertion and Reason are correct but Reason is not the correct explanation of the Assertion.
3 Assertion is correct but Reason is incorrect.
4 Both Assertion and Reason are incorrect.
BIOXII12: BIOTECHNOLOGY AND ITS APPLICATIONS

347736 Some of the steps involved in the production of Humulin are given below. Choose the correct sequence
(i) Synthesis of gene (DNA) for human insulin artificially
(ii) Culturing recombinant
E.coli
in bioreactors
(iii) Purification of humulin
(iv) Insertion of human insulin gene into plasmid
(v) Introduction of recombinant plasmid into
E.coli
(vi) Extraction of recombinant gene product from
E.coli

1 i, iii, v, vi, ii, iv
2 ii, i, iv, iii, v, vi
3 iii, v, ii, i, vi, iv
4 i, iv, v, ii, vi, iii
BIOXII12: BIOTECHNOLOGY AND ITS APPLICATIONS

347737 What is the merit of using the recombinant therapeutics instead of bovine insulin (from cow) in diabetic patients?

1 It leads to severe hyperglycemia
2 It is expensive
3 Do not induce unwanted immunological responses
4 It leads to severe hypoglycemia