Chromosomal Disorders
BIOXII05: PRINCIPLES OF INHERITANCE AND VARIATION

342049 Any change in sex chromosome is not involved in

1 Super female
2 Super male
3 Down’s syndrome
4 Turner’s syndrome
BIOXII05: PRINCIPLES OF INHERITANCE AND VARIATION

342050 Conditions of a karyotype 2n +1, 2n –1 and 2n + 2, 2n – 2 are called:

1 Aneuploidy
2 Polyploidy
3 Allopolyploidy
4 Monosomy
BIOXII05: PRINCIPLES OF INHERITANCE AND VARIATION

342051 Down syndrome is a genetic disorder which is characterised by the presence of an extra chromosome number

1 11
2 21
3 15
4 X
BIOXII05: PRINCIPLES OF INHERITANCE AND VARIATION

342052 Which statements about Down’s syndrome are
correct?
i. The frequency increases dramatically in
mother’s over the age of 40.
ii. The cause is a non-disjunction when
chromosomes do not separate during the
first meiotic division.
iii. Affected individuals have an extra
autosome.
iv. The long time lag between onset of meiosis
in ovarian tissue and its completion (at
ovulation) is most likely the reason for
increased incidence in older mothers.

1 i, ii, iii and iv
2 i and iv
3 i, ii and iii
4 ii, iii and iv
BIOXII05: PRINCIPLES OF INHERITANCE AND VARIATION

342053 The error in meiosis that produces a 47, XXY karyotype is best described by

1 Meiosis division I of maternal oogenesis
2 Meiosis division II of paternal spermatogenesis
3 Meiosis division II of maternal oogenesis
4 Meiosis division I of paternal spermatogenesis
BIOXII05: PRINCIPLES OF INHERITANCE AND VARIATION

342049 Any change in sex chromosome is not involved in

1 Super female
2 Super male
3 Down’s syndrome
4 Turner’s syndrome
BIOXII05: PRINCIPLES OF INHERITANCE AND VARIATION

342050 Conditions of a karyotype 2n +1, 2n –1 and 2n + 2, 2n – 2 are called:

1 Aneuploidy
2 Polyploidy
3 Allopolyploidy
4 Monosomy
BIOXII05: PRINCIPLES OF INHERITANCE AND VARIATION

342051 Down syndrome is a genetic disorder which is characterised by the presence of an extra chromosome number

1 11
2 21
3 15
4 X
BIOXII05: PRINCIPLES OF INHERITANCE AND VARIATION

342052 Which statements about Down’s syndrome are
correct?
i. The frequency increases dramatically in
mother’s over the age of 40.
ii. The cause is a non-disjunction when
chromosomes do not separate during the
first meiotic division.
iii. Affected individuals have an extra
autosome.
iv. The long time lag between onset of meiosis
in ovarian tissue and its completion (at
ovulation) is most likely the reason for
increased incidence in older mothers.

1 i, ii, iii and iv
2 i and iv
3 i, ii and iii
4 ii, iii and iv
BIOXII05: PRINCIPLES OF INHERITANCE AND VARIATION

342053 The error in meiosis that produces a 47, XXY karyotype is best described by

1 Meiosis division I of maternal oogenesis
2 Meiosis division II of paternal spermatogenesis
3 Meiosis division II of maternal oogenesis
4 Meiosis division I of paternal spermatogenesis
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BIOXII05: PRINCIPLES OF INHERITANCE AND VARIATION

342049 Any change in sex chromosome is not involved in

1 Super female
2 Super male
3 Down’s syndrome
4 Turner’s syndrome
BIOXII05: PRINCIPLES OF INHERITANCE AND VARIATION

342050 Conditions of a karyotype 2n +1, 2n –1 and 2n + 2, 2n – 2 are called:

1 Aneuploidy
2 Polyploidy
3 Allopolyploidy
4 Monosomy
BIOXII05: PRINCIPLES OF INHERITANCE AND VARIATION

342051 Down syndrome is a genetic disorder which is characterised by the presence of an extra chromosome number

1 11
2 21
3 15
4 X
BIOXII05: PRINCIPLES OF INHERITANCE AND VARIATION

342052 Which statements about Down’s syndrome are
correct?
i. The frequency increases dramatically in
mother’s over the age of 40.
ii. The cause is a non-disjunction when
chromosomes do not separate during the
first meiotic division.
iii. Affected individuals have an extra
autosome.
iv. The long time lag between onset of meiosis
in ovarian tissue and its completion (at
ovulation) is most likely the reason for
increased incidence in older mothers.

1 i, ii, iii and iv
2 i and iv
3 i, ii and iii
4 ii, iii and iv
BIOXII05: PRINCIPLES OF INHERITANCE AND VARIATION

342053 The error in meiosis that produces a 47, XXY karyotype is best described by

1 Meiosis division I of maternal oogenesis
2 Meiosis division II of paternal spermatogenesis
3 Meiosis division II of maternal oogenesis
4 Meiosis division I of paternal spermatogenesis
BIOXII05: PRINCIPLES OF INHERITANCE AND VARIATION

342049 Any change in sex chromosome is not involved in

1 Super female
2 Super male
3 Down’s syndrome
4 Turner’s syndrome
BIOXII05: PRINCIPLES OF INHERITANCE AND VARIATION

342050 Conditions of a karyotype 2n +1, 2n –1 and 2n + 2, 2n – 2 are called:

1 Aneuploidy
2 Polyploidy
3 Allopolyploidy
4 Monosomy
BIOXII05: PRINCIPLES OF INHERITANCE AND VARIATION

342051 Down syndrome is a genetic disorder which is characterised by the presence of an extra chromosome number

1 11
2 21
3 15
4 X
BIOXII05: PRINCIPLES OF INHERITANCE AND VARIATION

342052 Which statements about Down’s syndrome are
correct?
i. The frequency increases dramatically in
mother’s over the age of 40.
ii. The cause is a non-disjunction when
chromosomes do not separate during the
first meiotic division.
iii. Affected individuals have an extra
autosome.
iv. The long time lag between onset of meiosis
in ovarian tissue and its completion (at
ovulation) is most likely the reason for
increased incidence in older mothers.

1 i, ii, iii and iv
2 i and iv
3 i, ii and iii
4 ii, iii and iv
BIOXII05: PRINCIPLES OF INHERITANCE AND VARIATION

342053 The error in meiosis that produces a 47, XXY karyotype is best described by

1 Meiosis division I of maternal oogenesis
2 Meiosis division II of paternal spermatogenesis
3 Meiosis division II of maternal oogenesis
4 Meiosis division I of paternal spermatogenesis
BIOXII05: PRINCIPLES OF INHERITANCE AND VARIATION

342049 Any change in sex chromosome is not involved in

1 Super female
2 Super male
3 Down’s syndrome
4 Turner’s syndrome
BIOXII05: PRINCIPLES OF INHERITANCE AND VARIATION

342050 Conditions of a karyotype 2n +1, 2n –1 and 2n + 2, 2n – 2 are called:

1 Aneuploidy
2 Polyploidy
3 Allopolyploidy
4 Monosomy
BIOXII05: PRINCIPLES OF INHERITANCE AND VARIATION

342051 Down syndrome is a genetic disorder which is characterised by the presence of an extra chromosome number

1 11
2 21
3 15
4 X
BIOXII05: PRINCIPLES OF INHERITANCE AND VARIATION

342052 Which statements about Down’s syndrome are
correct?
i. The frequency increases dramatically in
mother’s over the age of 40.
ii. The cause is a non-disjunction when
chromosomes do not separate during the
first meiotic division.
iii. Affected individuals have an extra
autosome.
iv. The long time lag between onset of meiosis
in ovarian tissue and its completion (at
ovulation) is most likely the reason for
increased incidence in older mothers.

1 i, ii, iii and iv
2 i and iv
3 i, ii and iii
4 ii, iii and iv
BIOXII05: PRINCIPLES OF INHERITANCE AND VARIATION

342053 The error in meiosis that produces a 47, XXY karyotype is best described by

1 Meiosis division I of maternal oogenesis
2 Meiosis division II of paternal spermatogenesis
3 Meiosis division II of maternal oogenesis
4 Meiosis division I of paternal spermatogenesis