Biotechnological Applications in Medicine
BIOXII12: BIOTECHNOLOGY AND ITS APPLICATIONS

347714 Assertion :
ADA gene provides instructions for producing enzyme adenosine deaminase
Reason :
This enzyme is found throughout body, but is most active in the lymphocytes

1 Both Assertion and Reason are correct and Reason is the correct explanation of the Assertion.
2 Both Assertion and Reason are correct but Reason is not the correct explanation of the Assertion.
3 Assertion is correct but Reason is incorrect.
4 Both Assertion and Reason are incorrect.
BIOXII12: BIOTECHNOLOGY AND ITS APPLICATIONS

347715 The genetic defect Adenosine Deaminase (ADA) deficiency may be cured permanently by

1 Enzyme replacement therapy
2 Administering adenosine deaminase activators
3 Introducing bone marrow cells producing ADA into cells at early embryonic stages
4 Periodic infusion of genetically engineered lymphocytes having functional ADA C-DNA.
BIOXII12: BIOTECHNOLOGY AND ITS APPLICATIONS

347716 The site of production of ADA in the body is:

1 Erythrocytes
2 Lymphocytes
3 Blood plasma
4 Osteocytes
BIOXII12: BIOTECHNOLOGY AND ITS APPLICATIONS

347717 Which of the following statements is/are correct about Adenosine Deaminase (ADA) deficiency?
I. In the absence of adenosine deaminase enzyme, ATP metabolism is disturbed and neutrophils fail to function.
II. ADA deficiency is caused by the addition of the gene for ADA.
III. ADA patients can be permanently cured by bone marrow transplantation and enzyme replacement therapy.
IV. For permanent cure, the faulty genes are replaced with the genes isolated from the bone marrow cells producing ADA is introduced into cells in any stage

1 I, II and III
2 II and IV
3 I, III and IV
4 None of these
BIOXII12: BIOTECHNOLOGY AND ITS APPLICATIONS

347714 Assertion :
ADA gene provides instructions for producing enzyme adenosine deaminase
Reason :
This enzyme is found throughout body, but is most active in the lymphocytes

1 Both Assertion and Reason are correct and Reason is the correct explanation of the Assertion.
2 Both Assertion and Reason are correct but Reason is not the correct explanation of the Assertion.
3 Assertion is correct but Reason is incorrect.
4 Both Assertion and Reason are incorrect.
BIOXII12: BIOTECHNOLOGY AND ITS APPLICATIONS

347715 The genetic defect Adenosine Deaminase (ADA) deficiency may be cured permanently by

1 Enzyme replacement therapy
2 Administering adenosine deaminase activators
3 Introducing bone marrow cells producing ADA into cells at early embryonic stages
4 Periodic infusion of genetically engineered lymphocytes having functional ADA C-DNA.
BIOXII12: BIOTECHNOLOGY AND ITS APPLICATIONS

347716 The site of production of ADA in the body is:

1 Erythrocytes
2 Lymphocytes
3 Blood plasma
4 Osteocytes
BIOXII12: BIOTECHNOLOGY AND ITS APPLICATIONS

347717 Which of the following statements is/are correct about Adenosine Deaminase (ADA) deficiency?
I. In the absence of adenosine deaminase enzyme, ATP metabolism is disturbed and neutrophils fail to function.
II. ADA deficiency is caused by the addition of the gene for ADA.
III. ADA patients can be permanently cured by bone marrow transplantation and enzyme replacement therapy.
IV. For permanent cure, the faulty genes are replaced with the genes isolated from the bone marrow cells producing ADA is introduced into cells in any stage

1 I, II and III
2 II and IV
3 I, III and IV
4 None of these
BIOXII12: BIOTECHNOLOGY AND ITS APPLICATIONS

347714 Assertion :
ADA gene provides instructions for producing enzyme adenosine deaminase
Reason :
This enzyme is found throughout body, but is most active in the lymphocytes

1 Both Assertion and Reason are correct and Reason is the correct explanation of the Assertion.
2 Both Assertion and Reason are correct but Reason is not the correct explanation of the Assertion.
3 Assertion is correct but Reason is incorrect.
4 Both Assertion and Reason are incorrect.
BIOXII12: BIOTECHNOLOGY AND ITS APPLICATIONS

347715 The genetic defect Adenosine Deaminase (ADA) deficiency may be cured permanently by

1 Enzyme replacement therapy
2 Administering adenosine deaminase activators
3 Introducing bone marrow cells producing ADA into cells at early embryonic stages
4 Periodic infusion of genetically engineered lymphocytes having functional ADA C-DNA.
BIOXII12: BIOTECHNOLOGY AND ITS APPLICATIONS

347716 The site of production of ADA in the body is:

1 Erythrocytes
2 Lymphocytes
3 Blood plasma
4 Osteocytes
BIOXII12: BIOTECHNOLOGY AND ITS APPLICATIONS

347717 Which of the following statements is/are correct about Adenosine Deaminase (ADA) deficiency?
I. In the absence of adenosine deaminase enzyme, ATP metabolism is disturbed and neutrophils fail to function.
II. ADA deficiency is caused by the addition of the gene for ADA.
III. ADA patients can be permanently cured by bone marrow transplantation and enzyme replacement therapy.
IV. For permanent cure, the faulty genes are replaced with the genes isolated from the bone marrow cells producing ADA is introduced into cells in any stage

1 I, II and III
2 II and IV
3 I, III and IV
4 None of these
BIOXII12: BIOTECHNOLOGY AND ITS APPLICATIONS

347714 Assertion :
ADA gene provides instructions for producing enzyme adenosine deaminase
Reason :
This enzyme is found throughout body, but is most active in the lymphocytes

1 Both Assertion and Reason are correct and Reason is the correct explanation of the Assertion.
2 Both Assertion and Reason are correct but Reason is not the correct explanation of the Assertion.
3 Assertion is correct but Reason is incorrect.
4 Both Assertion and Reason are incorrect.
BIOXII12: BIOTECHNOLOGY AND ITS APPLICATIONS

347715 The genetic defect Adenosine Deaminase (ADA) deficiency may be cured permanently by

1 Enzyme replacement therapy
2 Administering adenosine deaminase activators
3 Introducing bone marrow cells producing ADA into cells at early embryonic stages
4 Periodic infusion of genetically engineered lymphocytes having functional ADA C-DNA.
BIOXII12: BIOTECHNOLOGY AND ITS APPLICATIONS

347716 The site of production of ADA in the body is:

1 Erythrocytes
2 Lymphocytes
3 Blood plasma
4 Osteocytes
BIOXII12: BIOTECHNOLOGY AND ITS APPLICATIONS

347717 Which of the following statements is/are correct about Adenosine Deaminase (ADA) deficiency?
I. In the absence of adenosine deaminase enzyme, ATP metabolism is disturbed and neutrophils fail to function.
II. ADA deficiency is caused by the addition of the gene for ADA.
III. ADA patients can be permanently cured by bone marrow transplantation and enzyme replacement therapy.
IV. For permanent cure, the faulty genes are replaced with the genes isolated from the bone marrow cells producing ADA is introduced into cells in any stage

1 I, II and III
2 II and IV
3 I, III and IV
4 None of these