347704
Gene therapy performed for correction of disorders
1 Is always a temporary cure
2 Could be permanent if gene is introduced in the early embryonic stages
3 Has not been tried for humans
4 Involves removal of defective genes & introduction of functional genes
Explanation:
In ADA deficiency, lymphocytes are extracted from blood, cultured and are introduced with functional ADA cDNA which are later introduced in patients. but this process is not immortal as the patient requires periodic infusion of such genetically engineered lymphocytes. However, if the gene isolate from marrow cells producing ADA is introduced into cells at early embryonic stages, it could be a permanent cure.
BIOXII12: BIOTECHNOLOGY AND ITS APPLICATIONS
347706
This image depicts human gene therapy Pick the disorders for which this technique have been applied successfully
1 Tumour Necrosis Factor
2 Adenosine deaminase deficiency
3 SCID
4 Both (2) and (3)
Explanation:
SCID / ADA deficiency
BIOXII12: BIOTECHNOLOGY AND ITS APPLICATIONS
347707
Statement A : ADA gene provides instructions for producing enzyme adenosine aminase Statement B : Adenosine aminase enzyme is found in the lymphocytes
1 Statement A is correct but Statement B is incorrect.
2 Statement A is incorrect but Statement B is correct.
3 Both statements are correct.
4 Both Statements are incorrect.
Explanation:
\(\mathrm{ADA}\) gene provides instructions for producing the enzyme adenosine deaminase. Enzyme is produced in all cells, but the highest levels of adenosine deaminase occur in immune system cells called lymphocytes, which develop in lymphoid tissues. This enzyme is produced in all cells, but the highest levels of adenosine deaminase occur in immune system cells called lymphocytes, which develop in lymphoid tissues. These lymphoid tissues include the thymus, which is a gland located behind the breastbone, and lymph nodes, which are found throughout the body. So,both statements are incorrect.
BIOXII12: BIOTECHNOLOGY AND ITS APPLICATIONS
347708
Which kind of therapy was given in 1990 to a four year old girl with adenosine deaminase (ADA) deficiency?
1 Gene therapy
2 Immunotherapy
3 Chemotherapy
4 Radiation therapy
Explanation:
The first clinical gene therapy was given in 1990 to a 4 year old girl with adenosine deaminase (ADA) deficiency.
347704
Gene therapy performed for correction of disorders
1 Is always a temporary cure
2 Could be permanent if gene is introduced in the early embryonic stages
3 Has not been tried for humans
4 Involves removal of defective genes & introduction of functional genes
Explanation:
In ADA deficiency, lymphocytes are extracted from blood, cultured and are introduced with functional ADA cDNA which are later introduced in patients. but this process is not immortal as the patient requires periodic infusion of such genetically engineered lymphocytes. However, if the gene isolate from marrow cells producing ADA is introduced into cells at early embryonic stages, it could be a permanent cure.
BIOXII12: BIOTECHNOLOGY AND ITS APPLICATIONS
347706
This image depicts human gene therapy Pick the disorders for which this technique have been applied successfully
1 Tumour Necrosis Factor
2 Adenosine deaminase deficiency
3 SCID
4 Both (2) and (3)
Explanation:
SCID / ADA deficiency
BIOXII12: BIOTECHNOLOGY AND ITS APPLICATIONS
347707
Statement A : ADA gene provides instructions for producing enzyme adenosine aminase Statement B : Adenosine aminase enzyme is found in the lymphocytes
1 Statement A is correct but Statement B is incorrect.
2 Statement A is incorrect but Statement B is correct.
3 Both statements are correct.
4 Both Statements are incorrect.
Explanation:
\(\mathrm{ADA}\) gene provides instructions for producing the enzyme adenosine deaminase. Enzyme is produced in all cells, but the highest levels of adenosine deaminase occur in immune system cells called lymphocytes, which develop in lymphoid tissues. This enzyme is produced in all cells, but the highest levels of adenosine deaminase occur in immune system cells called lymphocytes, which develop in lymphoid tissues. These lymphoid tissues include the thymus, which is a gland located behind the breastbone, and lymph nodes, which are found throughout the body. So,both statements are incorrect.
BIOXII12: BIOTECHNOLOGY AND ITS APPLICATIONS
347708
Which kind of therapy was given in 1990 to a four year old girl with adenosine deaminase (ADA) deficiency?
1 Gene therapy
2 Immunotherapy
3 Chemotherapy
4 Radiation therapy
Explanation:
The first clinical gene therapy was given in 1990 to a 4 year old girl with adenosine deaminase (ADA) deficiency.
347704
Gene therapy performed for correction of disorders
1 Is always a temporary cure
2 Could be permanent if gene is introduced in the early embryonic stages
3 Has not been tried for humans
4 Involves removal of defective genes & introduction of functional genes
Explanation:
In ADA deficiency, lymphocytes are extracted from blood, cultured and are introduced with functional ADA cDNA which are later introduced in patients. but this process is not immortal as the patient requires periodic infusion of such genetically engineered lymphocytes. However, if the gene isolate from marrow cells producing ADA is introduced into cells at early embryonic stages, it could be a permanent cure.
BIOXII12: BIOTECHNOLOGY AND ITS APPLICATIONS
347706
This image depicts human gene therapy Pick the disorders for which this technique have been applied successfully
1 Tumour Necrosis Factor
2 Adenosine deaminase deficiency
3 SCID
4 Both (2) and (3)
Explanation:
SCID / ADA deficiency
BIOXII12: BIOTECHNOLOGY AND ITS APPLICATIONS
347707
Statement A : ADA gene provides instructions for producing enzyme adenosine aminase Statement B : Adenosine aminase enzyme is found in the lymphocytes
1 Statement A is correct but Statement B is incorrect.
2 Statement A is incorrect but Statement B is correct.
3 Both statements are correct.
4 Both Statements are incorrect.
Explanation:
\(\mathrm{ADA}\) gene provides instructions for producing the enzyme adenosine deaminase. Enzyme is produced in all cells, but the highest levels of adenosine deaminase occur in immune system cells called lymphocytes, which develop in lymphoid tissues. This enzyme is produced in all cells, but the highest levels of adenosine deaminase occur in immune system cells called lymphocytes, which develop in lymphoid tissues. These lymphoid tissues include the thymus, which is a gland located behind the breastbone, and lymph nodes, which are found throughout the body. So,both statements are incorrect.
BIOXII12: BIOTECHNOLOGY AND ITS APPLICATIONS
347708
Which kind of therapy was given in 1990 to a four year old girl with adenosine deaminase (ADA) deficiency?
1 Gene therapy
2 Immunotherapy
3 Chemotherapy
4 Radiation therapy
Explanation:
The first clinical gene therapy was given in 1990 to a 4 year old girl with adenosine deaminase (ADA) deficiency.
347704
Gene therapy performed for correction of disorders
1 Is always a temporary cure
2 Could be permanent if gene is introduced in the early embryonic stages
3 Has not been tried for humans
4 Involves removal of defective genes & introduction of functional genes
Explanation:
In ADA deficiency, lymphocytes are extracted from blood, cultured and are introduced with functional ADA cDNA which are later introduced in patients. but this process is not immortal as the patient requires periodic infusion of such genetically engineered lymphocytes. However, if the gene isolate from marrow cells producing ADA is introduced into cells at early embryonic stages, it could be a permanent cure.
BIOXII12: BIOTECHNOLOGY AND ITS APPLICATIONS
347706
This image depicts human gene therapy Pick the disorders for which this technique have been applied successfully
1 Tumour Necrosis Factor
2 Adenosine deaminase deficiency
3 SCID
4 Both (2) and (3)
Explanation:
SCID / ADA deficiency
BIOXII12: BIOTECHNOLOGY AND ITS APPLICATIONS
347707
Statement A : ADA gene provides instructions for producing enzyme adenosine aminase Statement B : Adenosine aminase enzyme is found in the lymphocytes
1 Statement A is correct but Statement B is incorrect.
2 Statement A is incorrect but Statement B is correct.
3 Both statements are correct.
4 Both Statements are incorrect.
Explanation:
\(\mathrm{ADA}\) gene provides instructions for producing the enzyme adenosine deaminase. Enzyme is produced in all cells, but the highest levels of adenosine deaminase occur in immune system cells called lymphocytes, which develop in lymphoid tissues. This enzyme is produced in all cells, but the highest levels of adenosine deaminase occur in immune system cells called lymphocytes, which develop in lymphoid tissues. These lymphoid tissues include the thymus, which is a gland located behind the breastbone, and lymph nodes, which are found throughout the body. So,both statements are incorrect.
BIOXII12: BIOTECHNOLOGY AND ITS APPLICATIONS
347708
Which kind of therapy was given in 1990 to a four year old girl with adenosine deaminase (ADA) deficiency?
1 Gene therapy
2 Immunotherapy
3 Chemotherapy
4 Radiation therapy
Explanation:
The first clinical gene therapy was given in 1990 to a 4 year old girl with adenosine deaminase (ADA) deficiency.
