10. Enzymes and Enzyme Action
Biomolecules

185585 Which of the following statements regarding enzyme inhibition is correct -

1 Competitive inhibition is seen when a substrate competes with an enzyme for binding to an inhibitor protein
2 Non-competitive inhibitors often bind to the enzyme irreversibly
3 Competitive inhibition is seen when the substrate and the inhibitor compete for the active site on the enzyme
4 Non-competitive inhibition of an enzyme can be overcome by adding large amount of substrate
Biomolecules

185545 Assertion (A) : Active site of an enzyme is a crevice or pocket into which the substrate fits.
Reason (R) : In tertiary structure of protein chain when folds upon itself, the chain crisscrosses itself, and many cervices are formed.
The correct option among the following is:

1 (A) is true, (R) is true and (R) is the correct explanation of \((\mathrm{A})\)
2 (A) is true, (R) is true but (R) is not the correct explanation of \((\mathrm{A})\)
3 (A) is true but (R) is false
4 (A) is false but (R) is true
Biomolecules

185548 The term Enzyme was proposed by

1 W F Khune
2 E Fisher
3 D Koshland
4 E Buchner
Biomolecules

185549 Match the following lists:
| List-I | List-II | List-III |
| :---: | :---: | :---: |
| A) Coenzymes are organic compound | i) No structure similarities | I) Ribose-5 phosphate isomerase |
| B) Isomerases | ii) Differ from inorganic catalysis | II) During catalysis |
| C) Noncompetitive enzyme inhibition | iii) Catalyzing inter conversion of optical positional isomers | III) Operates at high Temperatu re also |
| D) Enzyme catalysts | iv) With the apoenzyme only as a transient | IV) Metal ion of copper |
The correct match is

1 A - iv, II B - iii, I C - i, IV D - 11,
2 A - iii, III B - ii, I C - iv, III D - 1,1
3 A - vi, II B - iii, I C - i, III D - ii, I
4 A - iii, III B - ii, IV C - iv, I D - I, I
Biomolecules

185551 Match the following-
| Enzymes | | Functions | |
| :--- | :--- | :---: | :--- |
| A. | Lyases | i. | Oxido reduction |
| B. | Isomerases | ii. | Link compounds |
| C. | Dehydrogenases | iii. | Transfer of
group |
| D. | Ligases | iv. | Interconversion |
| | | v. | Removal of
groups |
Options:

1 A - V B - iv C - i D - ii
2 A - iv B - v C - ii D - iii
3 A - iii B - ii C - iv D - i
4 A - i B - iii C - v D - iv
Biomolecules

185585 Which of the following statements regarding enzyme inhibition is correct -

1 Competitive inhibition is seen when a substrate competes with an enzyme for binding to an inhibitor protein
2 Non-competitive inhibitors often bind to the enzyme irreversibly
3 Competitive inhibition is seen when the substrate and the inhibitor compete for the active site on the enzyme
4 Non-competitive inhibition of an enzyme can be overcome by adding large amount of substrate
Biomolecules

185545 Assertion (A) : Active site of an enzyme is a crevice or pocket into which the substrate fits.
Reason (R) : In tertiary structure of protein chain when folds upon itself, the chain crisscrosses itself, and many cervices are formed.
The correct option among the following is:

1 (A) is true, (R) is true and (R) is the correct explanation of \((\mathrm{A})\)
2 (A) is true, (R) is true but (R) is not the correct explanation of \((\mathrm{A})\)
3 (A) is true but (R) is false
4 (A) is false but (R) is true
Biomolecules

185548 The term Enzyme was proposed by

1 W F Khune
2 E Fisher
3 D Koshland
4 E Buchner
Biomolecules

185549 Match the following lists:
| List-I | List-II | List-III |
| :---: | :---: | :---: |
| A) Coenzymes are organic compound | i) No structure similarities | I) Ribose-5 phosphate isomerase |
| B) Isomerases | ii) Differ from inorganic catalysis | II) During catalysis |
| C) Noncompetitive enzyme inhibition | iii) Catalyzing inter conversion of optical positional isomers | III) Operates at high Temperatu re also |
| D) Enzyme catalysts | iv) With the apoenzyme only as a transient | IV) Metal ion of copper |
The correct match is

1 A - iv, II B - iii, I C - i, IV D - 11,
2 A - iii, III B - ii, I C - iv, III D - 1,1
3 A - vi, II B - iii, I C - i, III D - ii, I
4 A - iii, III B - ii, IV C - iv, I D - I, I
Biomolecules

185551 Match the following-
| Enzymes | | Functions | |
| :--- | :--- | :---: | :--- |
| A. | Lyases | i. | Oxido reduction |
| B. | Isomerases | ii. | Link compounds |
| C. | Dehydrogenases | iii. | Transfer of
group |
| D. | Ligases | iv. | Interconversion |
| | | v. | Removal of
groups |
Options:

1 A - V B - iv C - i D - ii
2 A - iv B - v C - ii D - iii
3 A - iii B - ii C - iv D - i
4 A - i B - iii C - v D - iv
Biomolecules

185585 Which of the following statements regarding enzyme inhibition is correct -

1 Competitive inhibition is seen when a substrate competes with an enzyme for binding to an inhibitor protein
2 Non-competitive inhibitors often bind to the enzyme irreversibly
3 Competitive inhibition is seen when the substrate and the inhibitor compete for the active site on the enzyme
4 Non-competitive inhibition of an enzyme can be overcome by adding large amount of substrate
Biomolecules

185545 Assertion (A) : Active site of an enzyme is a crevice or pocket into which the substrate fits.
Reason (R) : In tertiary structure of protein chain when folds upon itself, the chain crisscrosses itself, and many cervices are formed.
The correct option among the following is:

1 (A) is true, (R) is true and (R) is the correct explanation of \((\mathrm{A})\)
2 (A) is true, (R) is true but (R) is not the correct explanation of \((\mathrm{A})\)
3 (A) is true but (R) is false
4 (A) is false but (R) is true
Biomolecules

185548 The term Enzyme was proposed by

1 W F Khune
2 E Fisher
3 D Koshland
4 E Buchner
Biomolecules

185549 Match the following lists:
| List-I | List-II | List-III |
| :---: | :---: | :---: |
| A) Coenzymes are organic compound | i) No structure similarities | I) Ribose-5 phosphate isomerase |
| B) Isomerases | ii) Differ from inorganic catalysis | II) During catalysis |
| C) Noncompetitive enzyme inhibition | iii) Catalyzing inter conversion of optical positional isomers | III) Operates at high Temperatu re also |
| D) Enzyme catalysts | iv) With the apoenzyme only as a transient | IV) Metal ion of copper |
The correct match is

1 A - iv, II B - iii, I C - i, IV D - 11,
2 A - iii, III B - ii, I C - iv, III D - 1,1
3 A - vi, II B - iii, I C - i, III D - ii, I
4 A - iii, III B - ii, IV C - iv, I D - I, I
Biomolecules

185551 Match the following-
| Enzymes | | Functions | |
| :--- | :--- | :---: | :--- |
| A. | Lyases | i. | Oxido reduction |
| B. | Isomerases | ii. | Link compounds |
| C. | Dehydrogenases | iii. | Transfer of
group |
| D. | Ligases | iv. | Interconversion |
| | | v. | Removal of
groups |
Options:

1 A - V B - iv C - i D - ii
2 A - iv B - v C - ii D - iii
3 A - iii B - ii C - iv D - i
4 A - i B - iii C - v D - iv
Biomolecules

185585 Which of the following statements regarding enzyme inhibition is correct -

1 Competitive inhibition is seen when a substrate competes with an enzyme for binding to an inhibitor protein
2 Non-competitive inhibitors often bind to the enzyme irreversibly
3 Competitive inhibition is seen when the substrate and the inhibitor compete for the active site on the enzyme
4 Non-competitive inhibition of an enzyme can be overcome by adding large amount of substrate
Biomolecules

185545 Assertion (A) : Active site of an enzyme is a crevice or pocket into which the substrate fits.
Reason (R) : In tertiary structure of protein chain when folds upon itself, the chain crisscrosses itself, and many cervices are formed.
The correct option among the following is:

1 (A) is true, (R) is true and (R) is the correct explanation of \((\mathrm{A})\)
2 (A) is true, (R) is true but (R) is not the correct explanation of \((\mathrm{A})\)
3 (A) is true but (R) is false
4 (A) is false but (R) is true
Biomolecules

185548 The term Enzyme was proposed by

1 W F Khune
2 E Fisher
3 D Koshland
4 E Buchner
Biomolecules

185549 Match the following lists:
| List-I | List-II | List-III |
| :---: | :---: | :---: |
| A) Coenzymes are organic compound | i) No structure similarities | I) Ribose-5 phosphate isomerase |
| B) Isomerases | ii) Differ from inorganic catalysis | II) During catalysis |
| C) Noncompetitive enzyme inhibition | iii) Catalyzing inter conversion of optical positional isomers | III) Operates at high Temperatu re also |
| D) Enzyme catalysts | iv) With the apoenzyme only as a transient | IV) Metal ion of copper |
The correct match is

1 A - iv, II B - iii, I C - i, IV D - 11,
2 A - iii, III B - ii, I C - iv, III D - 1,1
3 A - vi, II B - iii, I C - i, III D - ii, I
4 A - iii, III B - ii, IV C - iv, I D - I, I
Biomolecules

185551 Match the following-
| Enzymes | | Functions | |
| :--- | :--- | :---: | :--- |
| A. | Lyases | i. | Oxido reduction |
| B. | Isomerases | ii. | Link compounds |
| C. | Dehydrogenases | iii. | Transfer of
group |
| D. | Ligases | iv. | Interconversion |
| | | v. | Removal of
groups |
Options:

1 A - V B - iv C - i D - ii
2 A - iv B - v C - ii D - iii
3 A - iii B - ii C - iv D - i
4 A - i B - iii C - v D - iv
Biomolecules

185585 Which of the following statements regarding enzyme inhibition is correct -

1 Competitive inhibition is seen when a substrate competes with an enzyme for binding to an inhibitor protein
2 Non-competitive inhibitors often bind to the enzyme irreversibly
3 Competitive inhibition is seen when the substrate and the inhibitor compete for the active site on the enzyme
4 Non-competitive inhibition of an enzyme can be overcome by adding large amount of substrate
Biomolecules

185545 Assertion (A) : Active site of an enzyme is a crevice or pocket into which the substrate fits.
Reason (R) : In tertiary structure of protein chain when folds upon itself, the chain crisscrosses itself, and many cervices are formed.
The correct option among the following is:

1 (A) is true, (R) is true and (R) is the correct explanation of \((\mathrm{A})\)
2 (A) is true, (R) is true but (R) is not the correct explanation of \((\mathrm{A})\)
3 (A) is true but (R) is false
4 (A) is false but (R) is true
Biomolecules

185548 The term Enzyme was proposed by

1 W F Khune
2 E Fisher
3 D Koshland
4 E Buchner
Biomolecules

185549 Match the following lists:
| List-I | List-II | List-III |
| :---: | :---: | :---: |
| A) Coenzymes are organic compound | i) No structure similarities | I) Ribose-5 phosphate isomerase |
| B) Isomerases | ii) Differ from inorganic catalysis | II) During catalysis |
| C) Noncompetitive enzyme inhibition | iii) Catalyzing inter conversion of optical positional isomers | III) Operates at high Temperatu re also |
| D) Enzyme catalysts | iv) With the apoenzyme only as a transient | IV) Metal ion of copper |
The correct match is

1 A - iv, II B - iii, I C - i, IV D - 11,
2 A - iii, III B - ii, I C - iv, III D - 1,1
3 A - vi, II B - iii, I C - i, III D - ii, I
4 A - iii, III B - ii, IV C - iv, I D - I, I
Biomolecules

185551 Match the following-
| Enzymes | | Functions | |
| :--- | :--- | :---: | :--- |
| A. | Lyases | i. | Oxido reduction |
| B. | Isomerases | ii. | Link compounds |
| C. | Dehydrogenases | iii. | Transfer of
group |
| D. | Ligases | iv. | Interconversion |
| | | v. | Removal of
groups |
Options:

1 A - V B - iv C - i D - ii
2 A - iv B - v C - ii D - iii
3 A - iii B - ii C - iv D - i
4 A - i B - iii C - v D - iv